Yes it’s totally possible ! BLUART can be used to do TTL UART or RS485 <-> USB, the drivers are also available in your raspberry image, so it should be plug and play : )
Patrick is right that the BLUART will appear immediately as a serial port on the Raspberry Pi, however, that serial port won’t be forwarded to the surface. We have some tools available in Companion to forward that port through a UDP port, but it’s fairly challenging to create a virtual serial port at the surface.
So, if you’re fine communicating to a UDP port instead of a serial port at the surface then you can get this to work right now. We can explain more if that works for you.